Deferoxamine mesylate

CAS No. 138-14-7

Deferoxamine mesylate ( Desferrioxamine B mesylate;DFOM )

Catalog No. M11580 CAS No. 138-14-7

An iron chelator that binds iron and aluminium; increases HIF-1α transactivation in diabetes by preventing iron-catalyzed reactive oxygen stress.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Deferoxamine mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    An iron chelator that binds iron and aluminium; increases HIF-1α transactivation in diabetes by preventing iron-catalyzed reactive oxygen stress.
  • Description
    An iron chelator that binds iron and aluminium; increases HIF-1α transactivation in diabetes by preventing iron-catalyzed reactive oxygen stress.Other Indication Approved
  • Synonyms
    Desferrioxamine B mesylate;DFOM
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Aluminum;Iron
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    138-14-7
  • Formula Weight
    656.79
  • Molecular Formula
    C26H52N6O11S
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: ≥ 33 mg/mL
  • SMILES
    CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
  • Chemical Name
    Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxy-, methanesulfonate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Duscher D, et al. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):94-9.
2. Miyajima H, et al. Ann Neurol. 1997 Mar;41(3):404-7.
3. Choi EY, et al. J Immunol. 2004 Jun 1;172(11):7069-77.
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